Hypotonic Lysis of Mammalian Erythrocytes in Chlorpromazine Presence

Ekaterina A. Semionova, Nataliya A. Iershova, Nataliaya V. Orlova, Nataliya M. Shpakova

Abstract


Key words: hypotonic lysis, mammalian erythrocytes, chlorpromazine

 

Annotation: When studying hypotonic sensitivity of bovine, equine, canine and human erythrocytes the human and canine erythrocytes have been shown to be  more sensitive to the effect of hypotonic media. Chlorpromazine manifests a high antihemolytic activity under conditions of hypotonic lysis of mammalian erythrocytes. Maximal efficiency of chlorpromazine has been demonstrated for the bovine cells and minimal one was done for canine erythrocytes.


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