State Budgetary Healthcare Institution of Moscow Region, Moscow Regional Research and Clinical Institute M.F.Vladimirskiy's

Yulia Y. Chuksina, Viktor V. Yazdovskiy, Sergey V. Shevelev, Elena V. Kataeva, Anatolij K. Golenkov


Key Words: chronic lymphocytic leukemia, flow cytometry,   peripheral blood lymphocytes, minimal  residual  disease  


Annotation: The article presents an analysis of the prognostic significance of tumor cell immunophenotypic markers clone in patients with B-cell chronic lymphocytic leukemia in the dynamics of ongoing immuno-chemotherapy - R-FC (rituximab, fludarabine, cyclophosphamide) in the evaluation of minimal residual disease. Expression of CD25 on B-lymphocytes can be a predictor of the quality of remission, progression or recurrence of the disease in patients with CLL.


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