Evaluation of Immunomodulators Influence on Inhibited Associated Inactivated Vaccine Against Cattle Parainfluenza-3, Infectious Bovine Rhinotracheitis Virus and Bovine Viral Diarrhea-mucosal Disease Using Rabbits
Abstract
Respiratory and gastrointestinal diseases of young cattle are one of the main problems of veterinary science and practice. In the etiology of these diseases along with viral and bacterial agents play animal important role in immunodeficiency animals. In this regard, the use inactivated vaccines does induce full immunity in young herds.
Aim of this work was to study the effectiveness of combined use of inactivated against associated vaccine BP, BHV b BVDV with immunomodulators of chemical and biological origin using rabbits.
A complex hematological, biochemical, serological and immunological studies of blood samples on experimental and control groups of animal were performed. The study of blood serum for BP, BHV and BVDV showed an increase by 1,0-2,6 Log2 of post-vaccination antibody titers in the experimental group compared to the control one.
Associated using of immunomodulators of chemical and biological origin with ‘Inactivated emulsion associated vaccine against parainfluenza-3, infectious bovine rhinotracheitis virus and bovine viral diarrhea-mucosal disease promotes post-vaccination immunity tension and animal general resistance.
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